Bedroom Exposure to Airborne Allergens in the Chicago Area Using a Patient-Operated Sampling Device 

Indoor allergen exposure is an important risk factor for allergic respiratory disease.1 A recent European Academy of Allergy and Clinical Immunology position paper2 states that allergen exposure assessment should ideally be based on measurement of airborne concentration because this is a truer reflection of airway exposure. Because clinically relevant thresholds have not been established for all allergens tested, in a recent comprehensive US survey, part of the National Health and Nutrition Examination Survey (NHANES) 2005-2006 program, Salo et al3 used percentile cutoffs as a consistent analytic approach. The same group also defined morbidity threshold levels in dust for some allergens.4 They also state that exposure could be assessed more accurately with personal monitors. Sampling of the airborne compartment is a closer approximation to personal exposure. We have compared the performance of the Inspirotec airborne allergen sampling device with reference sampling methods, including settled dust.5 Settled dust collection has been the standard for many years2 because air sampling methods have been technically demanding and intrusive. The Inspirotec sampler now provides an air sampling method that is unobtrusive and requires no technical skill to operate.6

A smaller-scale study with the Inspirotec sampler, run by patients themselves,6demonstrated correlation of cat or dog presence in the home with the corresponding allergen in the bedroom. Bedrooms are considered an important site for allergen exposure because of the time spent in bed and the proximity of allergen reservoirs.3 …


Julian Gordon

Julian is a world renowned serial inventor who has made groundbreaking contributions to multiple fields of science. His group at Abbott Labs was responsible for developing lateral flow immunoassay technology, which led to the first home pregnancy tests. Prior to Abbott Labs, Julian’s group at Novartis (then CIBA-GEIGY) was responsible for inventing the Western Blot, an important method used today in molecular biology, biochemistry and immunogenetics for the characterization and detection of proteins. As a scientist, Julian is passionate about using evidence-based data to prevent human suffering. As he explains, “I know of no greater suffering than a mother in anguish about her child not being able to breathe normally – and not knowing what to do about it. I feel so fortunate to be part of an incredible team working to solve this problem.
Julian Gordon
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